A case of recurrent pulmonary inflammatory myofibroblastic tumor with aggressive metastasis after complete resection

Tuberc Respir Dis (Seoul). 2013 Oct;75(4):165-9. doi: 10.4046/trd.2013.75.4.165. Epub 2013 Oct 29.

Abstract

An inflammatory myofibroblastic tumor (IMT) is a rare disease entity reported to arise in various organs. It is thought to be a neoplastic or reactive inflammatory condition, controversially. The treatment of choice for myofibroblastic tumor is surgery, and recurrence is known to be rare. The optimal treatment method is not well-known for patients ineligible for surgery. We report a 47-year-old patient with aggressive recurrent IMT of the lungs. The patient had been admitted for an evaluation of back-pain two years after a complete resection of pulmonary IMT. Radiation therapy was performed for multiple bone recurrences, and the symptoms were improved. However the patient presented again with aggravated back-pain six months later. High-dose steroid and non-steroidal anti-inflammatory drugs were administered, but the disease progressed aggressively, resulting in spinal cord compression and metastasis to intra-abdominal organs. This is a very rare case of aggressively recurrent pulmonary IMT with multi-organ metastasis.

Keywords: Lung; Lung Neoplasms; Myofibroblasts; Neoplasm Metastasis; Recurrence.