Stochastic responses are not left to pure "chance"

Aggelos Banos; Marios Agelopoulos; Dimitris Thanos

doi:10.1016/j.cell.2013.10.002

Stochastic responses are not left to pure "chance"

Cell. 2013 Oct 24;155(3):499-502. doi: 10.1016/j.cell.2013.10.002. Epub 2013 Oct 24.

Authors

Aggelos Banos¹, Marios Agelopoulos, Dimitris Thanos

Affiliation

¹ Biomedical Research Foundation, Academy of Athens, 4 Soranou Efesiou Street, Athens 11527, Greece.

PMID: 24243008
DOI: 10.1016/j.cell.2013.10.002

Abstract

Many coregulated genes assemble in multigene complexes via stochastic inter- and intrachromosomal interactions. In this issue, Fanucchi et al. report that chromatin loop formation governs hierarchical cotranscription within a multigene complex.

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MeSH terms

Chromosomes*
Gene Expression Regulation*
Genetic Techniques*
Humans
Single-Cell Analysis*
Transcription, Genetic*