Silver-catalyzed cascade cyclization-stannylation of o-alkynylaniline derivatives with 2-tributylstannylfuran: an efficient synthesis of (3-indolyl)stannanes

Jun Liu; Xin Xie; Yuanhong Liu

doi:10.1039/c3cc46524a

Silver-catalyzed cascade cyclization-stannylation of o-alkynylaniline derivatives with 2-tributylstannylfuran: an efficient synthesis of (3-indolyl)stannanes

Chem Commun (Camb). 2013 Dec 28;49(100):11794-6. doi: 10.1039/c3cc46524a.

Authors

Jun Liu¹, Xin Xie, Yuanhong Liu

Affiliation

¹ State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling Ling Lu, Shanghai 200032, P. R. China. yhliu@mail.sioc.ac.cn.

PMID: 24213517
DOI: 10.1039/c3cc46524a

Abstract

A straightforward synthesis of (3-indolyl)stannanes through silver-catalyzed cyclization-stannylation of N-electron-withdrawing group-substituted o-alkynylanilines in the presence of 2-tributylstannylfuran is developed. This method offers several advantages such as no requirement of additional ligands, high efficiency and a wide reaction scope.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkynes / chemistry*
Aniline Compounds / chemistry*
Catalysis
Cyclization
Indoles / chemical synthesis*
Indoles / chemistry
Molecular Structure
Organotin Compounds / chemistry*
Silver / chemistry*

Substances

Alkynes
Aniline Compounds
Indoles
Organotin Compounds
Silver