Pediatric stroke outcome measure: predictor of multiple impairments in childhood stroke

Warren Lo; Anne L Gordon; Christine Hajek; Alison Gomes; Mardee Greenham; Vicki Anderson; Keith O Yeates; Mark T Mackay

doi:10.1177/0883073813503186

Pediatric stroke outcome measure: predictor of multiple impairments in childhood stroke

J Child Neurol. 2014 Nov;29(11):1524-30. doi: 10.1177/0883073813503186. Epub 2013 Oct 25.

Authors

Warren Lo¹, Anne L Gordon², Christine Hajek³, Alison Gomes⁴, Mardee Greenham⁵, Vicki Anderson⁶, Keith O Yeates⁷, Mark T Mackay⁸

Affiliations

¹ Division of Neurology, Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA warren.lo@nationwidechildrens.org.
² Paediatric Occupational Therapy Department, Paediatric Neuroscience, Evelina Children's Hospital, Guy's & St Thomas' Hospital NHS Foundation Trust, London, United Kingdom.
³ Department of Psychology, The Ohio State University, Columbus, Ohio, USA Center for Biobehavioral Health, Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
⁴ Critical Care & Neurosciences Research Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia Psychological Medicine, Monash University, Melbourne, Australia.
⁵ Critical Care & Neurosciences Research Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
⁶ Critical Care & Neurosciences Research Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia Department of Psychology, The Royal Children's Hospital, Melbourne, Australia School of Psychological Sciences, University of Melbourne, Melbourne, Australia.
⁷ Department of Psychology, The Ohio State University, Columbus, Ohio, USA Center for Biobehavioral Health, Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA Division of Psychology, Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA.
⁸ Critical Care & Neurosciences Research Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia Department of Neurology, The Royal Children's Hospital, Melbourne, Australia Department of Paediatrics, University of Melbourne, Parkville, Australia.

PMID: 24163399
DOI: 10.1177/0883073813503186

Abstract

The ability to anticipate deficits would help with implementation of interventions for children affected by stroke. The pediatric stroke outcome measure (measure) measures neurological impairment after stroke, but there has been little research examining the relationship between the measure and functional outcomes. We hypothesized the Measure correlates with cognitive and behavioral outcomes. Thirty-six children with stroke were assessed with the Measure, and tested for cognitive ability, problem behavior, adaptive behavior, and social participation. We examined the correlation between the total Measure and outcomes and determined how subscale scores associated with outcomes. Higher total Measure scores correlated with poorer outcomes in cognitive ability, problem behaviors, adaptive behaviors, and social participation. Specific subscale scores correlated with poorer outcomes in multiple domains. The total Measure can be used to anticipate poor outcomes in multiple domains after stroke and can help the clinician in the treatment of children as they recover.

Keywords: behavior; ischemic stroke; outcome measure; pediatric; social participation.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Brain Ischemia / diagnosis*
Brain Ischemia / physiopathology
Brain Ischemia / psychology
Brain Ischemia / therapy*
Case-Control Studies
Child
Child, Preschool
Female
Humans
Infant
Infant, Newborn
Intelligence Tests
Male
Neuropsychological Tests
Outcome Assessment, Health Care / methods*
Prognosis
Stroke / diagnosis*
Stroke / physiopathology
Stroke / psychology
Stroke / therapy*