Pseudothrombocytopenia observed with ethylene diamine tetra acetate and citrate anticoagulants, resolved using 37°C incubation and Kanamycin

Indian J Pathol Microbiol. 2013 Jul-Sep;56(3):306-8. doi: 10.4103/0377-4929.120407.

Abstract

Pseudothrombocytopenia (PTP) is defined by falsely low platelet counts on automated analyzers caused by in vitro phenomena including large platelet aggregates in blood samples. Diagnosis and resolution of PTP is crucial as it can lead to unwarranted interventions. We discuss a case of PTP in a pre-surgical setting, which was resolved using 37°C incubation and Kanamycin.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anticoagulants / metabolism*
  • Citric Acid / metabolism*
  • Diagnostic Errors
  • Edetic Acid / metabolism*
  • Humans
  • Kanamycin / metabolism*
  • Male
  • Specimen Handling / methods*
  • Temperature
  • Thrombocytopenia / diagnosis*

Substances

  • Anticoagulants
  • Citric Acid
  • Kanamycin
  • Edetic Acid