[Preclinical biomarker research and patient stratification of molecular target agents: the anti-angiogenic inhibitor Lenvatinib mesylate (E7080)]

Nihon Yakurigaku Zasshi. 2013 Oct;142(4):162-6. doi: 10.1254/fpj.142.162.
[Article in Japanese]
No abstract available

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors* / chemistry
  • Angiogenesis Inhibitors* / pharmacology
  • Angiogenesis Inhibitors* / therapeutic use
  • Animals
  • Biomarkers, Tumor*
  • Disease Models, Animal
  • Drug Evaluation, Preclinical
  • Humans
  • Melanoma / drug therapy
  • Molecular Targeted Therapy*
  • Mutation
  • Neoplasms / blood supply*
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • PTEN Phosphohydrolase / genetics
  • Phenylurea Compounds* / chemistry
  • Phenylurea Compounds* / pharmacology
  • Phenylurea Compounds* / therapeutic use
  • Precision Medicine
  • Proto-Oncogene Proteins B-raf / genetics
  • Quinolines* / chemistry
  • Quinolines* / pharmacology
  • Quinolines* / therapeutic use
  • Receptors, Vascular Endothelial Growth Factor / antagonists & inhibitors
  • Skin Neoplasms / drug therapy
  • Translational Research, Biomedical / trends

Substances

  • Angiogenesis Inhibitors
  • Biomarkers, Tumor
  • Phenylurea Compounds
  • Quinolines
  • Receptors, Vascular Endothelial Growth Factor
  • Proto-Oncogene Proteins B-raf
  • PTEN Phosphohydrolase
  • lenvatinib