Progress toward increasing fetal hemoglobin production in man: experience with 5-azacytidine and hydroxyurea

Ann N Y Acad Sci. 1985:445:218-24. doi: 10.1111/j.1749-6632.1985.tb17191.x.
No abstract available

Publication types

  • Clinical Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anemia, Sickle Cell / drug therapy*
  • Anemia, Sickle Cell / metabolism
  • Animals
  • Azacitidine / therapeutic use*
  • Azacitidine / toxicity
  • Bone Marrow / drug effects
  • Cells, Cultured
  • Clinical Trials as Topic
  • Erythropoiesis
  • Fetal Hemoglobin / biosynthesis*
  • Humans
  • Hydroxyurea / therapeutic use*
  • Hydroxyurea / toxicity
  • Reticulocytes / metabolism
  • Thalassemia / drug therapy*
  • Thalassemia / metabolism

Substances

  • Fetal Hemoglobin
  • Azacitidine
  • Hydroxyurea