Comparing EPI-743 treatment in siblings with Leber's hereditary optic neuropathy mt14484 mutation

Can J Ophthalmol. 2013 Oct;48(5):e130-3. doi: 10.1016/j.jcjo.2013.05.011.
No abstract available

Publication types

  • Case Reports
  • Comparative Study
  • Letter

MeSH terms

  • Child
  • DNA, Mitochondrial / genetics*
  • Humans
  • Male
  • Micronutrients / therapeutic use*
  • Mitochondrial Diseases / drug therapy*
  • Mitochondrial Diseases / genetics
  • Mutation*
  • Optic Atrophy, Hereditary, Leber / drug therapy*
  • Optic Atrophy, Hereditary, Leber / genetics
  • Pedigree
  • Polymerase Chain Reaction
  • Siblings
  • Treatment Outcome
  • Ubiquinone / analogs & derivatives*
  • Ubiquinone / therapeutic use
  • Visual Acuity / drug effects
  • Visual Fields / drug effects

Substances

  • DNA, Mitochondrial
  • Micronutrients
  • Ubiquinone
  • alpha-tocotrienol quinone