Rapamycin prolongs female reproductive lifespan

Li-li Luo; Jin-jie Xu; Yu-cai Fu

doi:10.4161/cc.26578

Rapamycin prolongs female reproductive lifespan

Cell Cycle. 2013 Nov 1;12(21):3353-4. doi: 10.4161/cc.26578. Epub 2013 Sep 23.

Authors

Li-li Luo¹, Jin-jie Xu, Yu-cai Fu

Affiliation

¹ Department of Gynecology and Obstetrics of the First Affiliated Hospital; Shantou University Medical College; Shantou, PR China.

No abstract available

Keywords: female rats; female reproductive lifespan; mTOR signaling; ovarian follicle development; primordial follicle activation; rapamycin; sirtuins.

Publication types

Editorial
Comment

MeSH terms

Animals
Female
Male
Ovarian Follicle / drug effects*
Sirolimus / pharmacology*
Sirtuin 2 / metabolism*
TOR Serine-Threonine Kinases / metabolism*

Substances

TOR Serine-Threonine Kinases
Sirtuin 2
Sirolimus