Genetic marker suitable for identification and genotyping of Plasmodium ovale curtisi and Plasmodium ovale wallikeri

J Clin Microbiol. 2013 Dec;51(12):4213-6. doi: 10.1128/JCM.01527-13. Epub 2013 Sep 25.

Abstract

We present a seminested PCR method that specifically discriminates between Plasmodium ovale curtisi and P. ovale wallikeri with high sensitivity. The test is based on species-specific amplification of a size-polymorphic fragment of the tryptophan-rich antigen gene, potra, which also permits discrimination of intraspecific sequence variants at this locus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA, Protozoan / chemistry
  • DNA, Protozoan / genetics*
  • Genes, Protozoan
  • Genetic Markers*
  • Molecular Sequence Data
  • Parasitology / methods*
  • Plasmodium ovale / classification*
  • Plasmodium ovale / genetics*
  • Polymerase Chain Reaction / methods*
  • Sequence Analysis, DNA

Substances

  • DNA, Protozoan
  • Genetic Markers

Associated data

  • GENBANK/KF018430
  • GENBANK/KF018431
  • GENBANK/KF018432
  • GENBANK/KF018433