A selective fluorescent chemosensor for phosphoserine

Org Biomol Chem. 2013 Nov 14;11(42):7387-92. doi: 10.1039/c3ob41677a.

Abstract

A fluorescent chemosensor for the detection of phosphoserine is reported. The ditopic sensor features a phosphate-coordinating zinc(II)-dipicolylamine (Zn(2+)-DPA) unit tethered to an amine-binding coumarin aldehyde fluorophore. With phosphoserine, the sensor demonstrates a 30-fold fluorescence enhancement under buffered aqueous conditions.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amines / chemistry
  • Chemistry Techniques, Analytical / instrumentation*
  • Fluorescent Dyes / chemistry*
  • Organometallic Compounds / chemistry*
  • Phosphates / chemistry
  • Phosphoserine / analysis*
  • Phosphoserine / chemistry
  • Picolinic Acids / chemistry

Substances

  • 2,2'-dipicolylamine
  • Amines
  • Fluorescent Dyes
  • Organometallic Compounds
  • Phosphates
  • Picolinic Acids
  • Phosphoserine