Decreased serum brain-derived neurotrophic factor levels are correlated with exercise intolerance in patients with heart failure

Int J Cardiol. 2013 Oct 12;168(5):e142-4. doi: 10.1016/j.ijcard.2013.08.073. Epub 2013 Aug 27.

Authors

Arata Fukushima¹, Shintaro Kinugawa, Tsuneaki Homma, Yoshihiro Masaki, Takaaki Furihata, Takashi Yokota, Shouji Matsushima, Takahiro Abe, Tadashi Suga, Shingo Takada, Tomoyasu Kadoguchi, Ryoichi Katsuyama, Koji Oba, Koichi Okita, Hiroyuki Tsutsui

Affiliation

¹ Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

PMID: 24029660
DOI: 10.1016/j.ijcard.2013.08.073

No abstract available

Keywords: Brain-derived neurotrophic factor; Depression; Exercise intolerance; Heart failure.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Biomarkers / blood
Brain-Derived Neurotrophic Factor / antagonists & inhibitors*
Brain-Derived Neurotrophic Factor / biosynthesis
Brain-Derived Neurotrophic Factor / blood
Down-Regulation / physiology*
Exercise / physiology*
Exercise Tolerance / physiology*
Female
Heart Failure / blood*
Humans
Male
Middle Aged
Stroke Volume / physiology

Substances

Biomarkers
Brain-Derived Neurotrophic Factor
BDNF protein, human