Abstract
A new type of apo-Tf functionalized nanochannel is developed to achieve the specific and selective binding and unbinding of Fe(3+) in a multiple and reversible manner via a protein-conformation-gating mechanism. This ion-responsive biomimetic nanochannel provides a simple, robust, and promising model for studying other biological processes.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Biomimetic Materials / chemistry
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Biomimetic Materials / metabolism*
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Ferric Compounds / chemistry
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Ferric Compounds / metabolism*
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Ions / chemistry
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Nanostructures / chemistry*
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Protein Binding
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Transferrin / chemistry
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Transferrin / metabolism*
Substances
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Ferric Compounds
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Ions
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Transferrin