Abstract
New classes of thia/oxa-azaspiro[3.4]octanes are synthesized through the implementation of robust and step-economic routes. The targeted spirocycles have been designed to act as novel, multifunctional, and structurally diverse modules for drug discovery. Furthermore, enantioselective approaches to the spirocycles are reported.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Aza Compounds / chemical synthesis*
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Aza Compounds / chemistry
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Drug Discovery*
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Molecular Structure
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Octanes / chemical synthesis*
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Octanes / chemistry
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Oxytocin / analogs & derivatives
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Spiro Compounds / chemical synthesis*
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Spiro Compounds / chemistry
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Stereoisomerism
Substances
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Aza Compounds
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Octanes
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Spiro Compounds
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Oxytocin
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oxytocin, Asp(5)-