Distal humerus atrophic nonunion in a child with osteogenesis imperfecta

J Pediatr Orthop. 2013 Oct-Nov;33(7):725-9. doi: 10.1097/BPO.0b013e3182a32e69.

Abstract

Atrophic nonunion of the distal humerus in children with osteogenesis imperfecta is a vexing and disabling problem. Traditional treatments, including casting, intramedullary nailing, plating and bone grafting have not been universally successful. We report on a case of successful treatment of one atrophic nonunion of the distal humerus in ad 2 year 10 month old child with type III OI who had failed more traditional treatments. The treatment used a combination of telescoping intramedullary nails, locking plate fixation and bone morphogenic protein.

Level of evidence: Level IV.

Publication types

  • Case Reports

MeSH terms

  • Bone Morphogenetic Proteins / administration & dosage*
  • Bone Nails
  • Bone Plates
  • Bone Transplantation / methods
  • Child, Preschool
  • Fracture Fixation, Internal / instrumentation
  • Fracture Fixation, Internal / methods
  • Fracture Fixation, Intramedullary / methods
  • Fractures, Ununited / surgery*
  • Humans
  • Humeral Fractures / etiology
  • Humeral Fractures / pathology
  • Humeral Fractures / surgery*
  • Male
  • Osteogenesis Imperfecta / complications*
  • Treatment Outcome

Substances

  • Bone Morphogenetic Proteins

Supplementary concepts

  • Osteogenesis imperfecta, type 3