Lithium-associated hyperthyroidism

Hosp Pract (1995). 2013 Aug;41(3):101-4. doi: 10.3810/hp.2013.08.1073.

Abstract

Goiters and hypothyroidism are well-known patient complications of the use of lithium for treatment of bipolar disease. However, the occurrence of lithium-induced hyperthyroidism is a more rare event. Many times, the condition can be confused with a flare of mania. Monitoring through serial biochemical measurement of thyroid function is critical in patients taking lithium. Hyperthyroidism induced by lithium is a condition that generally can be controlled medically without the patient having to discontinue lithium therapy, although in some circumstances, discontinuation of lithium therapy may be indicated. We report on a patient case of lithium-associated hyperthyroidism that resolved after discontinuation of the medication.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antimanic Agents / administration & dosage
  • Antimanic Agents / adverse effects*
  • Bipolar Disorder / drug therapy*
  • Diagnosis, Differential
  • Humans
  • Hyperthyroidism / chemically induced*
  • Hyperthyroidism / diagnosis
  • Hyperthyroidism / prevention & control*
  • Lithium Carbonate / administration & dosage
  • Lithium Carbonate / adverse effects*
  • Male
  • Thyroid Function Tests
  • Withholding Treatment

Substances

  • Antimanic Agents
  • Lithium Carbonate