Inappropriate use of antibiotics and Clostridium difficile infection

Am J Infect Control. 2013 Nov;41(11):1116-8. doi: 10.1016/j.ajic.2013.04.017. Epub 2013 Aug 7.

Abstract

We assessed appropriateness of preceding and concurrent antibiotics in 126 consecutive patients with hospital-associated Clostridium difficile infection. In 93 (73.8%) episodes, at least 1 preceding course of antibiotics was inappropriate. We provided feedback on concurrent antibiotics on the day of diagnosis during the final 8 months: 17 of 74 (23.0%) patients were on inappropriate antibiotics. Our recommendations were well received. Reviewing C difficile-infected patients allowed for identification of opportunities to improve antibiotic utilization and potentially improved patient outcomes.

Keywords: Antimicrobial stewardship; Health care-associated infection; Quality improvement.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use*
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / epidemiology*
  • Clostridium Infections / microbiology*
  • Diarrhea / epidemiology*
  • Diarrhea / microbiology*
  • Drug Utilization / statistics & numerical data
  • Humans
  • Male
  • Young Adult

Substances

  • Anti-Bacterial Agents