Prevention of venous thrombotic events in brain injury: review of current practices

Rambam Maimonides Med J. 2013 Jan 30;4(1):e0001. doi: 10.5041/RMMJ.10101. Print 2013 Jan.

Abstract

Venous thromboembolic event after traumatic brain injury represents a unique clinical challenge. Physicians must balance appropriate timing of chemoprophylaxis with risk of increased cerebral hemorrhage. Despite an increase in the literature since the 1990s, there are clear disparities in treatment strategies. This review discusses the prominent studies and subsequent findings regarding the topic with an attempt to establish recommendations using the existing evidence-based literature.

Keywords: Deep venous thrombosis; prophylaxis; traumatic brain injury; venous thromboembolic events.