Syphilis related to atypical oral lesions affecting an elderly man. a case report

Gerodontology. 2015 Mar;32(1):73-5. doi: 10.1111/ger.12047. Epub 2013 Jul 22.

Abstract

Objective: To present a case of oral syphilis in an old patient.

Background: Syphilis seems to be resurging mainly in the young. However, in the last twenty years, the elderly have become more susceptive to infectious diseases due to a more frequent use of sildenafil.

Clinical report: An 83-year-old man was referred to our clinic complaining of burning mouth. His medical history revealed papular lesions on chest and penis glans, which had been diagnosed and treated as scabiosis 2 months prior to our assessment. The intra-oral examination showed erosive and patch lesions on the bilateral lip commissures, the palate and the border of the tongue. Initially, oral herpes was suspected. However, both the serological test and the cytology were negative. Therefore, syphilis was hypothesised. Non-treponemic (VDRL) and treponemic tests (FTA-ABS) were reagent and secondary syphilis was confirmed. The treatment consisted of penicillin G benzathine 2.4 million IU/IM for 4 weeks. Both oral and skin lesions had complete remission.

Conclusion: The present case illustrates that syphilis should be suspected in old patients with oral atypical lesions.

Keywords: oral diseases; oral lesions; oral syphilis; syphilis.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Cardiolipins
  • Cholesterol
  • Diagnostic Errors* / prevention & control
  • Erectile Dysfunction / drug therapy
  • Fluorescent Treponemal Antibody-Absorption Test
  • Humans
  • Insecticides / therapeutic use
  • Ivermectin / therapeutic use
  • Male
  • Mouth / pathology*
  • Penicillin G Benzathine / administration & dosage
  • Penicillin G Benzathine / therapeutic use
  • Phosphatidylcholines
  • Scabies / diagnosis*
  • Scabies / drug therapy
  • Sildenafil Citrate / therapeutic use
  • Stomatitis, Herpetic / blood
  • Stomatitis, Herpetic / diagnosis*
  • Syphilis / blood
  • Syphilis / diagnosis*
  • Syphilis / drug therapy
  • Unsafe Sex
  • Urological Agents / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Cardiolipins
  • Insecticides
  • Phosphatidylcholines
  • Urological Agents
  • VDRL antigen
  • Ivermectin
  • Cholesterol
  • Sildenafil Citrate
  • Penicillin G Benzathine

Supplementary concepts

  • Syphilis, secondary