[Combined therapy of lapatinib and capecitabine effective against local recurrence of breast cancer]

Gan To Kagaku Ryoho. 2013 Jul;40(7):907-8.
[Article in Japanese]

Abstract

A 67-year-old woman after mastectomy was afflicted with local recurrence of left breast cancer during adjuvant trastuzumab therapy. Oral administration of lapatinib and capecitabine served to distinguish the recurrent tumor and also reduce the patient's distressing symptoms. This combined anti-cancer therapy may be available for patients with breast cancer for whom trastuzumab therapy was not adequately effective.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Capecitabine
  • Carcinoma, Intraductal, Noninfiltrating / drug therapy*
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Female
  • Fluorouracil / administration & dosage
  • Fluorouracil / analogs & derivatives
  • Humans
  • Lapatinib
  • Quinazolines / administration & dosage
  • Recurrence
  • Tomography, X-Ray Computed

Substances

  • Quinazolines
  • Lapatinib
  • Deoxycytidine
  • Capecitabine
  • Fluorouracil