Cortical mapping of 3D optical topography in infants

Adv Exp Med Biol. 2013:789:455-461. doi: 10.1007/978-1-4614-7411-1_61.

Abstract

Precise localisation of cortical activation in the early development of the infant brain remains unclear. It is challenging to co-register haemodynamic responses during functional activation in infants with the underlying anatomy of the brain. We used a multispectral imaging algorithm to reconstruct 3D optical topographic images of haemodynamic responses in an infant during voice processing. In this chapter, we present a method for co-registering 3D optical topography images reconstructed from functional activation data in infants onto anatomical brain images obtained from MRI structurals of the individual infants.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Brain / physiology*
  • Brain Mapping / methods*
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Infant
  • Magnetic Resonance Imaging / methods*