Porphyrin-based ytterbium complexes targeting anionic phospholipid membranes as selective biomarkers for cancer cell imaging

Chem Commun (Camb). 2013 Aug 21;49(65):7252-4. doi: 10.1039/c3cc43469a. Epub 2013 Jul 11.

Abstract

A porphyrin ytterbium complex (Yb-N) showed strong binding to phosphatidylserine and capability to differentiate cancer cells via targeting the anionic phospholipid membrane.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anions / chemistry
  • Coordination Complexes / chemistry*
  • HeLa Cells
  • Humans
  • Microscopy, Confocal
  • Phosphatidylserines / metabolism*
  • Porphyrins / chemistry*
  • Ytterbium / chemistry*

Substances

  • Anions
  • Coordination Complexes
  • Phosphatidylserines
  • Porphyrins
  • Ytterbium