Magnetic particle imaging (MPI) can be used as a fast diagnostic method for obtaining three-dimensional images from inside the body of small animals by the use of functionalized magnetic nanoparticles as tracer. Here, we present our scanner setup working at 10-kHz drive-field frequency to sample a field of view of 22 × 22 × 15 mm(3) with up to 32 volume images per second. A resolution of about 1 × 2 × 1 mm(3) is achieved with iron oxide nanoparticles (Resovist). We discuss the properties of the complete system for application in imaging small animals such as mice.