A mathematical model for the progression of dental caries

Math Med Biol. 2014 Dec;31(4):319-37. doi: 10.1093/imammb/dqt008. Epub 2013 Jun 26.

Abstract

A model for the progression of dental caries is derived. The analysis starts at the microscopic reaction and diffusion process. The local equations are averaged to derive a set of macroscopic equations. The global system includes features such as anisotropic diffusion and local changes in the geometry due to the melting of the enamel. The equations are then solved numerically. The simulations highlight the effect of anisotropy. In addition, we draw conclusions on the progression rate of caries, and discuss them in light of a number of experiments.

Keywords: caries; dentistry; mathematical model.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biofilms / growth & development
  • Dental Caries / etiology*
  • Dental Caries / metabolism
  • Dental Caries / pathology
  • Dental Enamel / metabolism
  • Dental Enamel / pathology
  • Disease Progression
  • Humans
  • Mathematical Concepts
  • Models, Dental*
  • Tooth Demineralization / etiology
  • Tooth Demineralization / metabolism
  • Tooth Demineralization / pathology