The first purification and unequivocal characterization of the radical form of the carbon-centered quinone ketoxy radical adduct

Chem Commun (Camb). 2013 Jul 21;49(57):6436-8. doi: 10.1039/c3cc42732c.

Abstract

We found, unexpectedly, that the radical form of the carbon-centered quinone ketoxy radical adduct with a recently developed spin-trapping agent BMPO can not only be directly detected and identified using HPLC/high resolution MS, but can also be isolated and purified using semi-preparative HPLC, enabling direct observation of its clean 6-line ESR signal.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon / chemistry*
  • Chromatography, High Pressure Liquid
  • Cyclic N-Oxides / chemistry*
  • Electron Spin Resonance Spectroscopy
  • Free Radicals / chemistry*
  • Mass Spectrometry
  • Quinones / chemistry*
  • Spin Trapping

Substances

  • 5-tert-butoxycarbonyl 5-methyl-1-pyrroline N-oxide
  • Cyclic N-Oxides
  • Free Radicals
  • Quinones
  • Carbon