Perspectives on liver and kidney transplantation in the human immunodeficiency virus-infected patient

Abstract

Human immunodeficiency virus (HIV) infection is no longer an absolute contraindication for transplantation for patients with advanced kidney and liver failure. This article reviews the outcome data in the solid organ transplantation of HIV-infected patients that led to a change in thinking by the transplant community. Several emerging issues are also reviewed, such as eligibility criteria, selection of optimal immunosuppression agents and antiretroviral therapy in this population, and management of coinfection with hepatitis B and hepatitis C after transplant.