Curricular frameworks are integral to educational programs and are viewed as the roadmaps of curriculum. This article describes the importance of curricular frameworks and the creation of an evidence-based curricular framework for a pediatric nurse residency program that had been in place for several years before framework development. The concepts of the framework include leadership, professional socialization, clinical reasoning, and technical skills. This article presents an evidence-based approach to build a curricular framework for a nurse residency program.