Does dietary salt induce autoimmunity?

Andrew L Croxford; Ari Waisman; Burkhard Becher

doi:10.1038/cr.2013.65

Does dietary salt induce autoimmunity?

Cell Res. 2013 Jul;23(7):872-3. doi: 10.1038/cr.2013.65. Epub 2013 May 7.

Authors

Andrew L Croxford¹, Ari Waisman, Burkhard Becher

Affiliation

¹ Institute of experimental Immunology, University of Zurich, Zurich, Switzerland.

Abstract

Two recent publications suggest that dietary salt may polarize TH17 cells and therefore increase the risk of developing autoimmune disease. Where low salt diets can readily be tested for their therapeutic effects in autoimmune disease, more work is needed to connect dietary salts with the development of immunopathology.

Publication types

Comment

MeSH terms

Animals
Cell Differentiation / drug effects*
Humans
Immediate-Early Proteins / metabolism*
Interleukin-17 / metabolism*
Protein Serine-Threonine Kinases / metabolism*
Sodium Chloride / pharmacology*
Th17 Cells / drug effects*
Th17 Cells / pathology*

Substances

Immediate-Early Proteins
Interleukin-17
Sodium Chloride
Protein Serine-Threonine Kinases