Organophosphate poisoning-induced acute renal failure

Pediatr Emerg Care. 2013 May;29(5):646-7. doi: 10.1097/PEC.0b013e31828e9e45.

Abstract

Background: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear.

Case: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function.

Conclusions: Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Acute Kidney Injury / therapy
  • Adolescent
  • Chlorpyrifos / toxicity*
  • Female
  • Hemofiltration
  • Humans
  • Insecticides / poisoning*
  • Organophosphate Poisoning / etiology*
  • Organophosphate Poisoning / rehabilitation
  • Paraparesis, Spastic / chemically induced
  • Peripheral Nervous System Diseases / chemically induced
  • Suicide, Attempted

Substances

  • Insecticides
  • Chlorpyrifos