Preoperative evaluation and perioperative management of right ventricular failure after left ventricular assist device implantation

Semin Cardiothorac Vasc Anesth. 2013 Dec;17(4):249-61. doi: 10.1177/1089253213488246. Epub 2013 May 2.

Abstract

Right ventricular (RV) failure continues to be a major cause of morbidity and mortality after left ventricular assist device (LVAD) implantation. Preoperative evaluation of RV function with a variety of clinical, laboratory, echocardiographic, and hemodynamic variables is essential to ensure appropriate patient selection for LVAD therapy but remains imperfect. Therefore, clinicians involved in the care of these patients need to be prepared to manage RV failure after LVAD placement. Perioperative management of RV failure after LVAD implantation requires minimization of intraoperative RV ischemia, maintenance of appropriate filling pressure, supportive therapy with pulmonary vasodilators and inotropes, and surgical interventions such as RV assist devices in select cases. This article reviews the incidence of RV failure with LVAD implantation, preoperative predictors of RV failure, and perioperative management strategies.

Keywords: heart failure; left ventricular assist device (LVAD); mechanical circulatory support; right ventricle.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Heart Failure / epidemiology
  • Heart Failure / etiology*
  • Heart Failure / physiopathology
  • Heart-Assist Devices*
  • Humans
  • Incidence
  • Patient Selection
  • Perioperative Care / methods
  • Preoperative Care / methods
  • Ventricular Dysfunction, Right / epidemiology
  • Ventricular Dysfunction, Right / etiology*
  • Ventricular Dysfunction, Right / physiopathology