Retinol-binding protein 4 levels are associated with measures of liver and renal function and oxidant/antioxidant status in obese children

Abstract

Serum retinol-binding protein 4 (RBP4) has been proposed as a metabolic risk factor in obesity. We found that RBP4 levels also were associated with liver enzymes and cystatin C. Oxidant stress is a significant feature in obese children with greater values of RBP4 that can mediate the development of comorbidities.

Keywords: CysC; Cystatin C; Estimated glomerular filtration rate; GGT; GSH; Gamma-glutamil transpeptidase; Glutathione; RBP4; Retinol-binding protein 4; eGFR.