Varicella-zoster virus acute myelitis in a patient with MS treated with natalizumab

Jennifer Yeung; Cécile Cauquil; Guillaume Saliou; Ghaida Nasser; Sophio Rostomashvili; David Adams; Marie Théaudin

doi:10.1212/WNL.0b013e3182918d27

Varicella-zoster virus acute myelitis in a patient with MS treated with natalizumab

Neurology. 2013 May 7;80(19):1812-3. doi: 10.1212/WNL.0b013e3182918d27. Epub 2013 Apr 24.

Authors

Jennifer Yeung¹, Cécile Cauquil, Guillaume Saliou, Ghaida Nasser, Sophio Rostomashvili, David Adams, Marie Théaudin

Affiliation

¹ AP-HP, Hôpital Bicêtre, France.

Abstract

We report a case of varicella-zoster virus (VZV) myelitis in a woman with relapsing-remitting multiple sclerosis (RRMS) receiving natalizumab, a humanized monoclonal antibody that induces an immunosuppression localized to the CNS.

Publication types

Case Reports

MeSH terms

Acute Disease
Adult
Antibodies, Monoclonal, Humanized / adverse effects*
Female
Herpes Zoster / chemically induced
Herpes Zoster / complications
Herpes Zoster / diagnosis*
Herpesvirus 3, Human / pathogenicity*
Humans
Multiple Sclerosis, Relapsing-Remitting / chemically induced
Multiple Sclerosis, Relapsing-Remitting / complications
Multiple Sclerosis, Relapsing-Remitting / diagnosis*
Myelitis / chemically induced
Myelitis / complications
Myelitis / diagnosis*
Natalizumab

Substances

Antibodies, Monoclonal, Humanized
Natalizumab