Left ventricular hypertrophy amplifies the QT, and Tp-e intervals and the Tp-e/ QT ratio of left chest ECG

Zhao Zhao; Zuyi Yuan; Yuqiang Ji; Yue Wu; Yinzhi Qi

doi:10.1016/S1674-8301(10)60011-5

Left ventricular hypertrophy amplifies the QT, and Tp-e intervals and the Tp-e/ QT ratio of left chest ECG

J Biomed Res. 2010 Jan;24(1):69-72. doi: 10.1016/S1674-8301(10)60011-5.

Authors

Zhao Zhao¹, Zuyi Yuan, Yuqiang Ji, Yue Wu, Yinzhi Qi

Affiliation

¹ Department of Cardiology, Key Laboratory of Environmental Genes Related to Diseases, Ministry of Education, the First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, China.

Abstract

Objective: To evaluate the changes in Tp-e interval (an interval from the peak to the end of the T wave), QT interval and Tp-e/QT ratio of the body surface ECG in patients with left ventricular hypertrophy (LVH).

Methods: The Tp-e interval and QT interval were measured on body surface ECGs in 42 patients without either hypertension or LVH (control group), 41 patients having hypertension but not LVH (non-LVH group), and 38 patients with both hypertension and LVH (LVH group).

Results: The mean corrected QT (QTc) interval, and mean corrected Tp-e[T(p-e)c] interval were significantly longer in the LVH group (0.430±0.021s vs. 0.409±0.019s, p < 0.01; 0.098±0.013s vs. 0.088±0.011s, respectively) than those in the control group. The Tp-e/QT ratio was also amplified in LVH group (0.232±0.028 vs.0.218±0.027) (p < 0.05).

Conclusion: LVH increased the QT interval, Tp-e interval and Tp-e/QT ratio of the body surface ECG.

Keywords: QT interval; Tp-e interval; arrhythmia; hypertension; left ventricular hypertrophy.