Quantitative analysis of cefalexin based on artificial neural networks combined with modified genetic algorithm using short near-infrared spectroscopy

Spectrochim Acta A Mol Biomol Spectrosc. 2013 May 15:109:308-12. doi: 10.1016/j.saa.2013.02.047. Epub 2013 Mar 6.

Abstract

In this paper, a novel chemometric method was developed for rapid, accurate, and quantitative analysis of cefalexin in samples. The experiments were carried out by using the short near-infrared spectroscopy coupled with artificial neural networks. In order to enhancing the predictive ability of artificial neural networks model, a modified genetic algorithm was used to select fixed number of wavelength.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Anti-Bacterial Agents / analysis*
  • Cephalexin / analysis*
  • Neural Networks, Computer
  • Spectroscopy, Near-Infrared / economics
  • Spectroscopy, Near-Infrared / methods*

Substances

  • Anti-Bacterial Agents
  • Cephalexin