Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections

J Clin Microbiol. 2013 Jun;51(6):1913-6. doi: 10.1128/JCM.00661-13. Epub 2013 Mar 20.

Abstract

We assessed the performance of the Ceeram and Altona assays, the first two commercially available hepatitis E virus (HEV) RNA assays, using serial dilutions of 4 HEV-positive reference samples (genotypes 3a, 3c, 3e, and 3f). Both assays provided good analytical sensitivity and high reproducibility for detecting genotype 3 HEV RNA.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hepatitis E / diagnosis*
  • Hepatitis E virus / genetics
  • Hepatitis E virus / isolation & purification*
  • Humans
  • RNA, Viral / genetics
  • RNA, Viral / isolation & purification*
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • RNA, Viral