Hypomelanosis of Ito and multiple naevoid hypertrichosis: rare cutaneous mosaicism

Abstract

Hypomelanosis of Ito and naevoid hypertrichosis are both uncommon disorders and their coexistence in the same patient is rarely described. Most previously reported patients, in addition to cutaneous lesions, had multiple neurological, musculoskeletal and other organ system involvements. We present the case of a 3-year-old girl with these two naevoid disorders at sites completely exclusive of each other and without any severe associated defects.

Keywords: hypomelanosis of Ito; mutation; naevoid hypertrichosis; twin spotting.