Large-scale, ultrapliable, and free-standing nanomembranes

Edward Kang; Jihee Ryoo; Gi Seok Jeong; Yoon Young Choi; Seung Min Jeong; Jongil Ju; Seok Chung; Shuichi Takayama; Sang-Hoon Lee

doi:10.1002/adma.201204619

Large-scale, ultrapliable, and free-standing nanomembranes

Adv Mater. 2013 Apr 18;25(15):2167-73. doi: 10.1002/adma.201204619. Epub 2013 Feb 19.

Authors

Edward Kang¹, Jihee Ryoo, Gi Seok Jeong, Yoon Young Choi, Seung Min Jeong, Jongil Ju, Seok Chung, Shuichi Takayama, Sang-Hoon Lee

Affiliation

¹ Department of Biomedical Engineering, College of Health Science, Korea University, Seoul, 136-703, Republic of Korea.

PMID: 23423854
DOI: 10.1002/adma.201204619

Abstract

The creation and characterization of large-area ultrathin highly pliable free-standing PDMS membranes and their application to the study of cellular epithelia is described. The ultra-thin membranes permitted the straight forward calculation of cell monolayer moduli, derived from measured stress-strain curves. These measurements allowed the unprecedented detection of cellular-level injury in the epithelia caused by the rupture of cell-cell tight junctions in response to stretching.

Publication types

Research Support, Non-U.S. Gov't