Long-term results and costs of muscle flap coverage with Ilizarov bone transport in lower limb salvage

J Orthop Trauma. 2013 Oct;27(10):576-81. doi: 10.1097/BOT.0b013e31828afde4.

Abstract

Objectives: To determine long-term outcomes and costs of Ilizarov bone transport and flap coverage for lower limb salvage.

Design: Case series with retrospective review of outcomes with at least 6-year follow-up.

Setting: Academic tertiary care medical center.

Patients: Thirty-four consecutive patients with traumatic lower extremity wounds and tibial defects who were recommended amputation but instead underwent complex limb salvage from 1993 to 2005.

Intervention: Flap reconstruction and Ilizarov bone transport.

Main outcome measurements: Outcomes assessed were flap complications, infection, union, malunion, need for chronic narcotics, ambulation status, employment status, and need for reoperations. A cost analysis was performed comparing this treatment modality to amputation.

Results: Thirty-four patients (mean age: 40 years) were included with 14 acute Gustilo IIIB/C defects and 20 chronic tibial defects (nonunion with osteomyelitis). Thirty-five muscle flaps were performed with 1 flap loss (2.9%). The mean tibial bone defect was 8.7 cm, mean duration of bone transport was 10.8 months, and mean follow-up was 11 years. Primary nonunion rate at the docking site was 8.8% and malunion rate was 5.9%. All patients achieved final union with no cases of recurrent osteomyelitis. No patients underwent future amputations, 29% required reoperations, 97% were ambulating without assistance, 85% were working full time, and only 5.9% required chronic narcotics. Mean lifetime cost per patient per year after limb salvage was significantly less than the published cost for amputation.

Conclusions: The long-term results and costs of bone transport and flap coverage strongly support complex limb salvage in this patient population.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Amputation, Surgical / economics
  • Amputation, Surgical / statistics & numerical data
  • Bone Transplantation / economics*
  • Bone Transplantation / statistics & numerical data
  • California / epidemiology
  • Combined Modality Therapy / economics
  • Combined Modality Therapy / statistics & numerical data
  • Comorbidity
  • Female
  • Fractures, Malunited
  • Health Care Costs / statistics & numerical data
  • Humans
  • Ilizarov Technique / economics*
  • Ilizarov Technique / statistics & numerical data
  • Longitudinal Studies
  • Lower Extremity / surgery
  • Male
  • Middle Aged
  • Myocutaneous Flap / economics*
  • Myocutaneous Flap / statistics & numerical data
  • Osteomyelitis / economics*
  • Osteomyelitis / epidemiology
  • Osteomyelitis / urine*
  • Prevalence
  • Retrospective Studies
  • Salvage Therapy / economics
  • Salvage Therapy / statistics & numerical data
  • Tibial Fractures / economics*
  • Tibial Fractures / epidemiology
  • Tibial Fractures / surgery*
  • Treatment Outcome
  • Young Adult