Genome Sequences of a Novel HIV-1 Circulating Recombinant Form, CRF55_01B, Identified in China

Xiaoxu Han; Minghui An; Weiqing Zhang; Weiping Cai; Xi Chen; Yutaka Takebe; Hong Shang

doi:10.1128/genomeA.00050-12

Genome Sequences of a Novel HIV-1 Circulating Recombinant Form, CRF55_01B, Identified in China

Genome Announc. 2013 Jan;1(1):e00050-12. doi: 10.1128/genomeA.00050-12. Epub 2013 Jan 24.

Authors

Xiaoxu Han¹, Minghui An, Weiqing Zhang, Weiping Cai, Xi Chen, Yutaka Takebe, Hong Shang

Affiliation

¹ Key Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.

Abstract

We report here a novel HIV-1 circulating recombinant form (CRF55_01B) composed of CRF01_AE and subtype B, with four recombination breakpoints in the pol gene. CRF55_01B was identified from three epidemiologically unlinked men having sex with men (MSM) in China, suggesting the ongoing generation of recombinants involving CRF01_AE and subtype B lineages among MSM in China.