Idebenone treatment in patients with OPA1-mutant dominant optic atrophy

Brain. 2013 Feb;136(Pt 2):e231. doi: 10.1093/brain/aws280. Epub 2013 Feb 6.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Child
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • GTP Phosphohydrolases / genetics*
  • Humans
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Optic Atrophy, Autosomal Dominant / drug therapy*
  • Optic Atrophy, Autosomal Dominant / genetics*
  • Pilot Projects
  • Retrospective Studies
  • Treatment Outcome
  • Ubiquinone / analogs & derivatives*
  • Ubiquinone / pharmacology
  • Ubiquinone / therapeutic use
  • Visual Acuity / drug effects
  • Visual Acuity / physiology
  • Young Adult

Substances

  • Ubiquinone
  • GTP Phosphohydrolases
  • OPA1 protein, human
  • idebenone