Failure-free survival of the Durata defibrillator lead

Europace. 2013 Jul;15(7):1002-6. doi: 10.1093/europace/eut010. Epub 2013 Feb 1.

Abstract

Aims: Given design similarities and a common manufacturer, there have been suspicions regarding the Durata™ defibrillator (ICD) lead, in the aftermath of the Riata™ class I recall. We therefore examined the failure-free survival rates of the Durata™ compared with the Riata™ and Sprint Quattro™ ICD leads.

Methods and results: All patients (n = 2475) implanted with a Durata (n = 828), Riata [n = 627; 8 Fr. (n = 472) and 7 Fr. (n = 155)], or Sprint Quattro (n = 1020) leads at our institution were included and Kaplan-Meier failure-free survival curves were constructed for all leads. Lead failure was defined as electrical malfunction resulting in lead replacement, excluding dislodgements or perforations. Annual electrical failure rates were 0.3%, 1.7, and 0.3% for the Durata, Riata, and Sprint Quattro leads, respectively (P < 0.0001 for the comparison of Durata to Riata and P = 0.1.0 for the comparison of Durata to Sprint Quattro). The failure-free survival of the Durata lead was significantly better than that of the Riata lead (P < 0.0001) and similar to that of the Sprint Quattro (P = 0.94). The 7 Fr. Riata ST lead had better survival compared with the 8 Fr. Riata lead (P = 0.050) and comparable survival with the Durata lead (P = 0.12).

Conclusion: The Durata lead failure-free survival is significantly better than the 8 Fr. Riata, albeit at a shorter follow-up time. Riata and comparable with that of the 7 Fr. Riata ST and the Sprint Quattro ICD leads. These data provide an insight into the mechanism of electrical failure of Riata leads and have implications for patient management.

Keywords: Defibrillator lead; Durata; Failure; Riata.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Chi-Square Distribution
  • Defibrillators, Implantable*
  • Device Removal
  • Disease-Free Survival
  • Electric Countershock / adverse effects
  • Electric Countershock / instrumentation*
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Pennsylvania
  • Prosthesis Design
  • Prosthesis Failure*
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome