Accelerated phosphorus magnetic resonance spectroscopic imaging using compressed sensing

Nurten C Askin; Berna Atis; Esin Ozturk-Isik

doi:10.1109/EMBC.2012.6346128

Accelerated phosphorus magnetic resonance spectroscopic imaging using compressed sensing

Annu Int Conf IEEE Eng Med Biol Soc. 2012:2012:1106-9. doi: 10.1109/EMBC.2012.6346128.

Authors

Nurten C Askin¹, Berna Atis, Esin Ozturk-Isik

Affiliation

¹ Biomedical Engineering Department, Yeditepe University, Istanbul, Turkey. ceren.askin@yeditepe.edu.tr

PMID: 23366089
DOI: 10.1109/EMBC.2012.6346128

Abstract

This study aims at assessing the performance of compressed sensing method for faster phosphorus magnetic resonance spectroscopic imaging ((31)P-MRSI) of human brain. A simulated 2D (31)P-MRSI dataset containing a tumor region and a healthy region was created based on the metabolite peak intensities and ratios of a volunteer dataset acquired at 3T. k-space data was randomly undersampled, and reconstructed using compressed sensing algorithm. This simulation study showed that compressed sensing reconstruction could be applied for faster (31)P-MRSI. Future studies will measure the performance of compressed sensing reconstruction for (31)P-MRSI in volunteers and patients with brain tumors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Brain Neoplasms / metabolism*
Brain Neoplasms / pathology*
Diagnostic Imaging / methods
Humans
Magnetic Resonance Spectroscopy / methods*
Models, Biological*
Phosphorus / metabolism*
Sensitivity and Specificity

Substances

Phosphorus