Two cases of Ruminococcus gnavus bacteremia associated with diverticulitis

J Clin Microbiol. 2013 Apr;51(4):1334-6. doi: 10.1128/JCM.03382-12. Epub 2013 Jan 30.

Abstract

We report two cases of bacteremia with the anaerobic bacterium Ruminococcus gnavus. In both cases, the bacteremia was associated with diverticular disease. Preliminary conventional identification suggested peptostreptococci, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) analysis did not produce scores high enough for species identification. Finally, the bacteria were identified by 16S rRNA gene sequencing.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Bacteremia / complications
  • Bacteremia / diagnosis*
  • Bacteremia / microbiology
  • Bacteremia / pathology*
  • Bacterial Typing Techniques
  • Cluster Analysis
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Diverticulitis / complications
  • Diverticulitis / diagnosis*
  • Diverticulitis / microbiology
  • Diverticulitis / pathology*
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / microbiology
  • Gram-Positive Bacterial Infections / pathology*
  • Humans
  • Male
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Ruminococcus / chemistry
  • Ruminococcus / genetics
  • Ruminococcus / isolation & purification*
  • Ruminococcus / physiology
  • Sequence Analysis, DNA
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S