Ciprofloxacin-resistant Aeromonas hydrophila cellulitis following leech therapy

Carmen L Giltner; April M Bobenchik; Daniel Z Uslan; Jaime G Deville; Romney M Humphries

doi:10.1128/JCM.03217-12

Ciprofloxacin-resistant Aeromonas hydrophila cellulitis following leech therapy

J Clin Microbiol. 2013 Apr;51(4):1324-6. doi: 10.1128/JCM.03217-12. Epub 2013 Jan 30.

Authors

Carmen L Giltner¹, April M Bobenchik, Daniel Z Uslan, Jaime G Deville, Romney M Humphries

Affiliation

¹ David Geffen School of Medicine, Department of Pathology, University of California, Los Angeles, California, USA.

Abstract

We report a case of surgical site infection with ciprofloxacin-resistant Aeromonas hydrophila following leech therapy. Antimicrobial and genetic analyses of leech and patient isolates demonstrated that the resistant isolates originated from the leech gut microbiota. These data suggest that ciprofloxacin monotherapy as a prophylaxis regimen prior to leech therapy may not be effective in preventing infection.

Publication types

Case Reports

MeSH terms

Aeromonas hydrophila / drug effects
Aeromonas hydrophila / isolation & purification*
Animals
Anti-Bacterial Agents / pharmacology*
Cellulitis / diagnosis*
Cellulitis / microbiology
Cellulitis / pathology
Child
Ciprofloxacin / pharmacology*
Drug Resistance, Bacterial*
Female
Gastrointestinal Tract / microbiology
Gram-Negative Bacterial Infections / diagnosis*
Gram-Negative Bacterial Infections / microbiology
Gram-Negative Bacterial Infections / pathology
Hirudo medicinalis / microbiology
Humans
Leeching / adverse effects*
Surgical Wound Infection / diagnosis
Surgical Wound Infection / microbiology
Surgical Wound Infection / pathology

Substances

Anti-Bacterial Agents
Ciprofloxacin