Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation

Neuropathol Appl Neurobiol. 2013 Aug;39(5):580-4. doi: 10.1111/nan.12022.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Amyotrophic Lateral Sclerosis / genetics
  • Amyotrophic Lateral Sclerosis / metabolism*
  • Amyotrophic Lateral Sclerosis / pathology
  • Atrophy
  • Brain / metabolism*
  • Brain / pathology
  • Female
  • Humans
  • Inclusion Bodies / metabolism*
  • Inclusion Bodies / pathology
  • Mutation
  • RNA-Binding Protein FUS / genetics
  • RNA-Binding Protein FUS / metabolism*
  • beta Karyopherins / genetics
  • beta Karyopherins / metabolism*

Substances

  • RNA-Binding Protein FUS
  • TNPO1 protein, human
  • beta Karyopherins