The mechanism of caseinolytic protease (ClpP) inhibition

Angew Chem Int Ed Engl. 2013 Mar 4;52(10):3009-14. doi: 10.1002/anie.201204690. Epub 2013 Jan 30.

Authors

Malte Gersch¹, Felix Gut, Vadim S Korotkov, Johannes Lehmann, Thomas Böttcher, Marion Rusch, Christian Hedberg, Herbert Waldmann, Gerhard Klebe, Stephan A Sieber

Affiliation

¹ Center for Integrated Protein Science Munich, Technische Universität München, Department of Chemistry, Institute of Advanced Studies, Lichtenbergstrasse 4, 85747 Garching, Germany.

PMID: 23361916
DOI: 10.1002/anie.201204690

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Endopeptidase Clp / antagonists & inhibitors*
Enzyme Activation / drug effects
Humans
Models, Molecular
Protease Inhibitors / chemistry*
Protease Inhibitors / pharmacology

Substances

Protease Inhibitors
Endopeptidase Clp
CLPX protein, human