Dual-nanogold-linked bio-barcodes with superstructures for in situ amplified electronic detection of low-abundance proteins

Mol Biosyst. 2013 Apr 5;9(4):622-5. doi: 10.1039/c3mb25536k.

Abstract

A novel and nonenzyme immunosensing protocol is proposed for ultrahighly sensitive detection of low-abundance-proteins (carcinoembryonic antigen as a model) using dual nanogold-linked complementary bio-barcodes with superstructures for in situ amplified electronic signals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques* / methods
  • Carcinoembryonic Antigen / chemistry
  • DNA / chemistry
  • Gold* / chemistry
  • Immunoassay / methods
  • Metal Nanoparticles* / chemistry
  • Metal Nanoparticles* / ultrastructure
  • Nucleic Acid Hybridization / methods
  • Proteins / chemistry*

Substances

  • Carcinoembryonic Antigen
  • Proteins
  • Gold
  • DNA