Hyperpigmentation, neutrophilic alveolitis, and erythema nodosum resulting from minocycline

J Am Acad Dermatol. 1990 May;22(5 Pt 2):959-62. doi: 10.1016/0190-9622(90)70135-5.

Abstract

Hyperpigmentation, pulmonary infiltration, and erythema nodosum occurred in a patient receiving long-term minocycline therapy. Bronchoalveolar lavage revealed both a neutrophilic and an eosinophilic alveolitis. The pulmonary and systemic symptoms promptly resolved after discontinuation of minocycline.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Bronchoalveolar Lavage Fluid / analysis
  • Erythema Nodosum / chemically induced*
  • Erythema Nodosum / pathology
  • Female
  • Humans
  • Minocycline / administration & dosage
  • Minocycline / adverse effects*
  • Neutrophils
  • Pigmentation Disorders / chemically induced*
  • Pigmentation Disorders / pathology
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / pathology
  • Tetracyclines / adverse effects*

Substances

  • Tetracyclines
  • Minocycline