Exacerbation of psoriatic skin lesions in a patient with Alzheimer disease receiving gamma-secretase inhibitor

J Am Acad Dermatol. 2013 Feb;68(2):e46-8. doi: 10.1016/j.jaad.2012.07.012.
No abstract available

Publication types

  • Case Reports
  • Clinical Trial, Phase III
  • Letter

MeSH terms

  • Aged
  • Alanine / adverse effects
  • Alanine / analogs & derivatives*
  • Alzheimer Disease / drug therapy*
  • Amyloid Precursor Protein Secretases / antagonists & inhibitors*
  • Azepines / adverse effects*
  • Humans
  • Middle Aged
  • Psoriasis / chemically induced*

Substances

  • Azepines
  • N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide
  • Amyloid Precursor Protein Secretases
  • Alanine