Abstract
Bacillus cereus (B. cereus) is a Gram-positive rod that is widely distributed in the environment and can be a cause of food poisoning. We herein present a case of B. cereus necrotizing pneumonia in a patient with nephrotic syndrome under corticosteroid treatment after developing transient gastroenteritis symptoms. B. cereus was isolated from bronchial lavage fluid and transbronchial biopsy specimens. A multiplex polymerase chain reaction analysis of the toxin genes revealed a strain possessing enterotoxicity. The patient recovered after one week of intravenous meropenem followed by a combination of oral moxifloxacin and clindamycin. B. cereus is a pathogen that causes necrotizing pneumonia in immunocompromised hosts.
MeSH terms
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Adrenal Cortex Hormones / therapeutic use
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Adult
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Anti-Bacterial Agents / therapeutic use
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Aza Compounds / administration & dosage
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Bacillus cereus / immunology
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Bacillus cereus / isolation & purification*
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Biopsy, Needle
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Bronchoalveolar Lavage Fluid / cytology
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Clindamycin / administration & dosage
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Drug Therapy, Combination
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Fluoroquinolones
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Follow-Up Studies
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Gram-Positive Bacterial Infections / complications
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Gram-Positive Bacterial Infections / diagnosis*
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Gram-Positive Bacterial Infections / immunology
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Humans
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Immunocompromised Host*
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Immunohistochemistry
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Male
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Meropenem
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Moxifloxacin
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Necrosis / pathology
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Nephrotic Syndrome / complications
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Nephrotic Syndrome / diagnosis
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Nephrotic Syndrome / drug therapy
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Nephrotic Syndrome / immunology*
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Pneumonia, Bacterial / drug therapy
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Pneumonia, Bacterial / microbiology*
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Pneumonia, Bacterial / pathology*
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Quinolines / administration & dosage
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Radiography, Thoracic / methods
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Risk Assessment
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Severity of Illness Index
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Thienamycins / administration & dosage
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Tomography, X-Ray Computed / methods
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Treatment Outcome
Substances
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Adrenal Cortex Hormones
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Anti-Bacterial Agents
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Aza Compounds
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Fluoroquinolones
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Quinolines
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Thienamycins
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Clindamycin
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Meropenem
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Moxifloxacin